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Pathological Achilles Tendon Rupture in a Patient with Undiagnosed Alkaptonuria
Alkaptonuria (AKU) is a rare autosomal recessive disorder that is caused due to the deficient activity of hom*ogentisate1, 2‐dioxygenase which results in increased levels of hom*ogentisic acid (HGA) and its oxidized product benzoquinone acetic acid (BQA), which form polymerized deposits resulting in a bluish‐black discoloration of the cartilage as well as degeneration, inflammation and calcification of the tendons, ligaments and large joints and increased bone res...
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