CRANBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

Overview

Cranberry (Vaccinium macrocarpon) is an evergreen shrub that grows in bogs in North America. It produces dark red fruits that contain salicylic acid.

Chemicals in cranberries keep bacteria from sticking to the cells in the urinary tract. But they don't seem to be able to remove bacteria that are already stuck to these cells. This might explain why cranberry helps prevent urinary tract infections (UTIs), but doesn't help treat them.

People commonly use cranberry to prevent UTIs. Cranberry is also used for kidney stones, enlarged prostate, the common cold, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse cranberry with cramp bark, lingonberry, or uva ursi. These are sometimes also called cranberry but they are not the same.

Uses & Effectiveness ?

Possibly Effective for

  • Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs). Taking certain cranberry products by mouth seems to help prevent UTIs in adult females, children, and people at risk for developing UTIs due to certain surgeries or radiation treatment. But it doesn't seem to help people with neurogenic bladder, a condition caused by a spinal cord injury. Cranberry products do not seem prevent UTIs in elderly or pregnant people. It's important to note that while cranberry might help prevent UTIs in some people, it shouldn't be used to treat UTIs.

There is interest in using cranberry for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Cranberry is commonly consumed in foods. Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people.

Special Precautions and Warnings

When taken by mouth: Cranberry is commonly consumed in foods. Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people. Pregnancy and breast-feeding: Cranberry is commonly consumed in foods. There isn't enough reliable information to know if cranberry is safe to use in larger amounts when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Children: Cranberry is commonly consumed in foods. There isn't enough reliable information to know if cranberry is safe to use as medicine or what the side effects might be.

Aspirinallergy: Cranberries contain significant amounts of salicylic acid. Salicylic acid is similar to aspirin. Avoid drinking large quantities of cranberry juice if you are allergic to aspirin.

Diabetes: Some cranberry juice products are sweetened with extra sugar. If you have diabetes, stick with cranberry products that are sweetened with artificial sweeteners.

Kidney stones: Cranberry juice and cranberry extracts contain a large amount of a chemical called oxalate. Since oxalate is found in kidney stones, cranberry might increase the risk of kidney stones. If you have a history of kidney stones, stay on the safe side and avoid taking cranberry extract products or drinking a lot of cranberry juice.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Warfarin (Coumadin) interacts with CRANBERRY

    Warfarin is used to slow blood clotting. Cranberry might increase how long warfarin is in the body, and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. Your warfarin dose might need to be changed.

  • Atorvastatin (Lipitor) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down atorvastatin. This might increase the effects and side effects of atorvastatin. Avoid drinking large amounts of cranberry juice if you are taking atorvastatin.

  • Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CRANBERRY

    Some medications are changed and broken down by the liver. Cranberry might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Nifedipine (Procardia) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down nifedipine. Drinking cranberry juice while taking nifedipine might increase the effects and side effects of nifedipine.

    Minor Interaction

    Be watchful with this combination

  • Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CRANBERRY

    Some medications are changed and broken down by the liver. Cranberry might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Diclofenac (Voltaren, others) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down diclofenac. Drinking cranberry juice while taking diclofenac might increase the effects and side effects of diclofenac.

Dosing

Cranberry is commonly consumed in the diet in juices, jellies, sauces, and other foods.

As medicine, cranberry dried powder has most often been used by adults in doses of 250-1500 mg by mouth daily for up to 6 months. Cranberry extract has most often been used in doses of 120-1600 mg by mouth daily for 12 weeks. And cranberry juice drinks are often used in doses of 120-750 mL daily for up to 90 days. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circ*mstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

CRANBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

FAQs

What precautions should be taken with cranberry extract? ›

Cranberry has relatively high levels of oxalate, chemicals that may raise the risk of kidney stones in some people. If you have kidney stones, talk to your doctor before taking cranberry supplements or drinking a lot of cranberry juice. DO NOT use cranberry if you already have a UTI.

What medications cannot be taken with cranberry? ›

by Drugs.com

Cranberry may increase the anticoagulant effect from blood thinners like warfarin and lead to bruising or bleeding. If you take an oral blood thinner, check with your doctor before consuming large amounts of cranberry or cranberry juice.

What are the side effects of cranberry? ›

Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people.

Are cranberry supplements safe to take everyday? ›

They are packed with antioxidants and can help reduce the frequency of urinary tract infections in some people. Also, they may promote heart health, improve blood sugar control, boost immunity and protect against cancer, cavities and stomach ulcers. Dosages of up to 1,500 mg per day are safe for most.

Does cranberry extract affect blood pressure? ›

Cranberry extracts may also help with cancer protection, teeth and gum health, lower blood pressure, obesity, and inflammation.

Does cranberry detox the liver? ›

The presence of several potent antioxidants in cranberry juice like Proanthocyanidins have a strong iron chelating capability, which make it easy for the liver to remove toxins from the body.

Why is cranberry juice not good for kidneys? ›

Cranberry juice is high in oxalates, which can increase your risk of calcium oxalate kidney stones. This is because oxalates bind to calcium when you consume a lot of them, especially if you're already prone to kidney stones ( 3 , 4 ).

Can I take Tylenol with cranberry? ›

Interactions between your drugs

No interactions were found between cranberry and Tylenol Cold + Mucus Severe.

Is cranberry hard on the liver? ›

Cranberry products have not been linked to serum aminotransferase elevations or to instances of clinically apparent liver injury with jaundice.

Who should not eat cranberries? ›

Cranberries are packed with antioxidants and have several health benefits. If possible, eat them fresh to avoid the added sugars found in dried fruits and juices. Don't eat cranberries if you take blood thinners, get frequent kidney stones, or are allergic to aspirin.

What organ is cranberry good for? ›

Cranberries provide a good source of various vitamins and antioxidants. Historically, Native Americans used cranberries as a treatment for bladder and kidney diseases, while early settlers from England used them to treat poor appetite, stomach complaints, blood disorders, and scurvy.

What does cranberry do to the human body? ›

Consuming cranberries can prevent tooth decay and gum disease, inhibit urinary tract infections, reduce inflammation in the body, maintain a healthy digestion system, and decrease cholesterol levels [2,5,9,10].

Which is better, cranberry juice or cranberry pills? ›

Studies have pointed out that due to the added sugars and water that dilute the cranberry juice, cranberry capsules are a more effective alternative. In fact, it turns out that the active ingredient in cranberries that helps prevent E. coli from turning into an infection may not even be present in cranberry juice!

What is the best brand of cranberry pills? ›

Best OTC Choices in Cranberry Supplements
Rank desc ascMedication desc ascActive Ingredients desc asc
#1Nature's Bounty CranberryVitamin C Vitamin E Cranberry concentrate
#2NOW Foods Cranberry CapsVitamin C Cranberry
#3Solaray CranActinVitamin C Cranberry
#4Nature's Way Cranberry FruitCranberry
6 more rows
Mar 13, 2024

Do cranberry pills cure a urinary tract infection? ›

Cranberries don't seem to work for everyone. And they don't treat UTIs that you already have. The American College of Obstetrics and Gynecology says that unsweetened cranberry juice and cranberry supplements may make UTIs less likely, but that it's not yet clear how much you need to take and for how long.

Should cranberry extract be taken with or without food? ›

Although cranberry extract can be taken on an empty stomach, it is recommended that the capsules are taken alongside meals, especially ones that contain another source of vitamin C, as this will help to augment the absorption of the polyphenol qualities that people are seeking.

Does cranberry extract interfere with antibiotics? ›

Analyses showed that the cranberry extract increases bacterial sensitivity to antibiotics by acting in two ways. First, it makes the bacterial cell wall more permeable to the antibiotic, and second, it interferes with the mechanism used by the bacteria to pump out the antibiotic.

How much cranberry extract is too much? ›

The recommended daily dose ranges widely, typically 120 to 1600 mg as capsules daily or as 300 to 900 mL of cranberry juice. Cranberry is generally well tolerated without adverse events. With high doses, minor side effects may include diarrhea, abdominal discomfort and nausea.

Is cranberry supplement a blood thinner? ›

The high concentration of salicylic acid in cranberries provides similar effects as aspirin, which is a salicylate. Drinking cranberry juice or taking cranberry supplements can help prevent blood clots by acting as a blood thinner.

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